5-bromo-2-iodopyrimidine

Description

5-bromo-2-iodopyrimidine is a pyrimidine-based building block. Ring heteroatoms redistribute electron density, dipole and hydrogen-bonding capacity relative to an all-carbon analogue – which is the reason a heterocyclic core gets chosen where a carbocycle would be geometrically equivalent but electronically wrong.

Key data

• Catalogue code: KC1024
• CAS number: 183438-24-6
• Molecular formula: C4H2BrIN2
• Molecular weight: 284.88 g/mol
• Category: Heterocycles

What the substitution pattern does

Two ring nitrogens give pyrimidine a substantial in-plane dipole and remove electron density from the ring. Both effects are exploited deliberately: the dipole couples to applied fields, and the electron deficiency activates the ring toward nucleophilic substitution at the 2- and 4-positions.

Typical applications

• materials chemistry requiring a polar, planar ring system
• heterocyclic cores for mesogens with tailored dipole and polarisability
• ligand and pharmacophore construction in discovery chemistry
• fluorescent probes and laser dyes where the coumarin motif applies
• cross-coupling substrates carrying a pre-installed heteroatom

Ordering

This compound is supplied to order. Pricing depends on quantity and on the specification you need, so it is quoted rather than listed – send an enquiry stating the quantity and any purity or analytical requirement, and you will receive a written quotation.

Please quote CAS 183438-24-6 or catalogue code KC1024 when enquiring, so that the correct isomer is supplied.

Handling and documentation

Supplied for laboratory and industrial use by trained personnel only. Not for use as a medicine, food, cosmetic or biocide, and not for administration to humans or animals. Safety documentation is issued with the order; this page is not a source of hazard information.